Environmental pollution in the Anthropocene is composed by multiple stressors and complex mixtures of pollutants. The main aim of the course is to define and analyze exposure pathways in the environment to multiple pollutants and stressors (the Eco-Exposome). The course provides a large-scale perspective (Basinal) and will focus on presenting different pollution sources, monitoring and research of pollution, movement and fate of pollutants, and the eco-toxicological potential of pollutant mixtures.